Hasnain says:

“But what concerns us is what we’re seeing in the clinic every day: More young people, otherwise healthy with no genetic syndrome, being diagnosed with very advanced stages of gastrointestinal cancers. For men under 50, colorectal cancer is now the leading cause of cancer-related death, surpassing central nervous system tumors as well as lung cancers. In women under 50, it is now the second leading cause of cancer death. These are concerning numbers and we are all working hard to understand why this is happening.

What’s your sense of possible culprits?

We see this generational change — a “birth cohort effect” — in the rise of young-onset cancers. That leads us to suspect that a recent change in an environmental exposure or a combination of exposures is contributing to the rise. The main hypothesis is that some not-as-yet-identified environmental exposure is affecting individuals, starting in early life. The exposure perhaps occurs in utero, in infancy, or during childhood. That then predisposes us to cancers at an earlier age. A lot of work has been focused on what the environmental exposures may be and what they might be doing biologically to lead to cancer development at a younger age.”

Hasnain says:

“Gaza has become the expression of a legitimacy crisis for an Anglo-American political class who preside over already fragile systems that deliver less and less to their populations, and whose main offering is that the alternative is worse. Things may look stable, but underneath lurk managed discontents about costs of living, diminished social mobility and the ravages wreaked by rightwing governments to which centrists provide no real answer.”

Hasnain says:

I remember reading the original tweet thread and finding the story hilarious. Really cool to see the name change is now official!

“But Nasser couldn’t just leave it there. “By then, I don’t know, I had sort of fallen for this thing,” he tells Sky & Telescope. “I think if it had been labeled on the poster as 2002VE, for whatever weird mystical reason, I don’t think I would have fallen in love with it quite as hard as I did.” But somehow the funny-sounding name Zoozve had really struck a chord with him.

“So I was like, ok, can we actually change it?” Nasser set about learning the somewhat arcane process for the formal naming of asteroids, and asked for Skiff’s help.”

Hasnain says:

Rafah is being bombed right nkw - 1.5 million refugees suffering from a genocide, conveniently timed to happen during the Super Bowl. I have no words, just pain.

:(

Hasnain says:

“Hind’s mother, Wissam Hamada, added: “I will question before God on Judgment Day those who heard my daughter’s cries for help and did not save her.””

Hasnain says:

More fun time stuff.

“SPTP can offer significantly simpler, faster, and more reliable synchronization. Similar to G.8265.1 and G.8275.2 it provides excellent synchronization quality using a different set of parameters. Simplification comes with certain tradeoffs, such as missing signaling messages, that users need to be aware of and decide”

Hasnain says:

Learnt way too much about time and protocols from this one.

“We believe PTP will become the standard for keeping time in computer networks in the coming decades. That’s why we’re deploying it on an unprecedented scale. We’ve had to take a critical look at our entire infrastructure stack — from the GNSS antenna down to the client API — and in many cases we’ve even rebuilt things from scratch.”

Hasnain says:

“His fellow academic, Prof Yusuf Jubril, explains that their colleagues find it strange: "Society make us think someone is too big for certain roles and it's not true.
"What he is doing is not humiliating but commendable, and I hope others learn from him."”

Hasnain says:

“Even a highway network paved completely with quiet asphalt and driven upon exclusively by appropriately sized electric vehicles, however, is not enough to make roadways places of repose. As one biologist told Goldfarb in “Crossings,” “the best way to preserve quiet habitat for wildlife is to not build the damn road … Once you do, you’re in big trouble.” Goldfarb’s book considers the barriers that keep animals off the highway, so they don’t become roadkill. These barriers must also keep the dull shriek of the highway within its boundaries.”

Hasnain says:

“It might seem insane to take a bet on inexperienced people, especially in the context of hiring them to work at a company in our current layoff-heavy market. I certainly don’t suggest populating an entire company with this type of person. But every great high growth company needs at least some high potential and unconventional people. Transformative companies need people to 1) do something crazy, time consuming, and novel without the burden of too much past experience and yet 2) have enough wisdom and experience to distinguish the special sauce of the business from the actually destructive craziness. It’s easier to find and evaluate the experienced folks who can do the latter thing. It’s almost impossible to find the right inexperienced ones to do the former, who are inventive and original and yet also disciplined. They don’t have any obvious past experience that helps you figure out how special they are.”