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SARS-CoV-2 Infection Weakens Immune-Cell Response to Vaccination

The magnitude and quality of a key immune cell’s response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found. In addition, the level of this key immune...

Click to view the original at niaid.nih.gov

Hasnain says:

This is…. Not great. I don’t have high hopes in our public health systems nowadays but I hope action is finally taken at some point before it’s too late.

“Taken together, the investigators write, these findings suggest that SARS-CoV-2 infection damages the CD8+ T cell response, an effect akin to that observed in earlier studies showing long-term damage to the immune system after infection with viruses such as hepatitis C or HIV. The new findings highlight the need to develop vaccination strategies to specifically boost antiviral CD8+ T cell responses in people previously infected with SARS-CoV-2, the researchers conclude. “

Posted on 2023-03-21T23:32:41+0000